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====== SFB/TRR393 : Trajectories of Affective Disorders======
 
===== Cognitive-Emotional Mechanisms of Symptom Change =====

The SFB/TRR 393 Trajectories of Affective Disorders: Cognitive-Emotional Mechanisms of Symptom Change is a joint project of the Universities of Marburg, Münster, Dresden, and Bonn and KIT Karlsruhe. Funded by the DFG (Deutsche Forschungsgemeinschaft), the first funding period has recently started on October 1st, 2024.

Within the SFB/TRR 393, across 24 projects, we aim to define distinct trajectories of affective disorders in humans and animals, identify antecedents and correlates of recurrence and remission, determine cognitive-emotional and neurobiological mechanisms of symptom change, and develop and probe mechanism-based interventions.

Homepage: [[https://www.uni-marburg.de/en/trr-393/about-us]]

===== General information =====

==== Onboarding application form ====

https://redcap.link/sfb393_onoffboarding


==== Data deletion / anonymization form ====

https://redcap.link/393_datenloeschung 


===== How Do I Get Support? =====

==== E-Mail ====

For IT-related issues you can contact the INF project at this mail address:\\
<trr393-inf@groups.tu-dresden.de> \\

For general questions you might want to use the general mailing list of the project:\\ <trr393_all@lists.uni-marburg.de>\\


**❗️ To contact us please use your offical institutional email address.**
 
==== Neurocloud Chat ====

You can contact most regular employees using the Talk App available on the [[https://neurocloud.zih.tu-dresden.de/index.php/apps/spreed/|Neurocloud]].

===== Information about the Information Infrastructure Services =====

  * [[tools:redcap|Data collection (REDCap)]]
  * [[tools:pams|Participant Management (PAMS)]]
  * [[tools:neurocloud|Neurocloud]]
  * [[tools:xnat|Image archiving and pipelining (XNAT)]]


===== Information specific for the partner institutions =====

  * [[institution:nic|TU Dresden (NIC)]]
  * [[institution:ukd|Universitätsklinikum Dresden (UKD)]]
  * [[institution:marburg|Philipps-Universität Marburg]]
  * [[institution:muenster|Universität Münster]]
  * [[institution:kit|Karlsruhe Institute of Technology (KIT)]]
  * [[institution:bielefeld|Universität Bielefeld]]
===== Other information =====

  * [[projects:trr393:pams|Participant management in SFB393]]
  * [[projects::trr393:inflection_signal|Inflection Signal]]


===== Detailed information about the subprojects =====

^ Number ^ Shortcut ^ Name                                                                         ^ Location         ^ Principal Investigators ^
| 11101  | [[projects:trr393:s01|S01]]    | Mobile infrastructure      | KIT    | Ulrich Ebner-Priemer |
| 11102  | [[projects:trr393:s02|S02]]    | Longitudinal intermittent sampling  | Marburg\\ Dresden | Nina Alexander\\ Andrea Pfennig |
| 11103  | [[projects:trr393:s03|S03]]    | Machine learning development and infrastructure platform | Münster\\ Marburg| Tim Hahn\\ Hamidreza Jamalabadi |
| 11111  | [[projects:trr393:a01|A01]]    | Longitudinal monitoring in affective disorders                               | KIT\\ Münster    | Ulrich Ebner-Priemer\\  Tim Hahn |
| 11112  | [[projects:trr393:a02|A02]]    | Longitudinal trajectories of brain changes as mediators of course of illness | Dresden\\ Münster| Eva Mennigen\\ Udo Dannlowski |
| 11113  | [[[[projects:trr393:a03|A03]]    | Dissecting the contribution of immune cell activation dependent neuronal connectivity changes to disease trajectories in major depression | Münster\\ Bonn | Michael Ziller\\ Andreas Forstner |
| 11114  | [[projects:trr393:a04|A04]]    | Brain network characterization of symptom changes using intense sampling | Münster\\ Marburg|Katharina Koch\\ Igor Nenadić |
| 11115  | [[projects:trr393:a05|A05]]    | Molecular and immunological characterization of symptom changes and course of illness using intense sampling | Münster\\ Dresden| Judith Alferink\\ Carmine Pariante |
| 11116  | [[projects:trr393:a06|A06]]    | Intense sampling for symptom changes on the trajectory from bipolar high risk to bipolar disorder | Dresden |Julia Martini\\ Andrea Pfennig |
| 11121  | [[projects:trr393:b01|B01]]    | Emotion perception, emotion regulation variability and flexibility modulate the effect of stressful life events on the course of illness in affective disorders | Marburg\\ Dresden|Andreas Jansen\\ Stefan Ehrlich|
| 11122  | [[projects:trr393:b02|B02]]    | Characterization of life event-triggered inflection signals and emotion regulation in a mouse model | Münster\\ Dresden| Kay Jüngling\\ Nadine Bernhardt |
| 11123  | [[projects:trr393:b03|B03]]    | The mechanistic role of expectation in the development of symptom changes in patients with MDD | Marburg | Benjamin Straube\\ Hamidreza Jamalabadi|
| 11124  | [[projects:trr393:b04|B04]]    | Identifying inflection signals through continuous long-term monitoring of changes in affect and expectations in genetic rat models for affective disorders | Marburg | Markus Wöhr\\ Carsten Culmsee |
| 11125  | [[projects:trr393:b05|B05]]    | Social interaction predictors of symptom change in major depression | Marburg\\ Dresden| Nina Alexander\\ Philipp Kanske |
| 11126  | [[projects:trr393:b06|B06]]    | Brain activity correlates of socio-affective communication and cognition under genetic risk modulated through stressful life events |Dresden\\ Marburg |Nadine Bernhardt\\ Markus Wöhr|
| 11127  | [[projects:trr393:b07|B07]]    | Linking cognitive-behavioural rhythms to brain oscillations, cognition and disease trajectories | Münster\\ \\ Dresden | Ida Wessing\\  Joachim Groß\\ Philipp Ritter |
| 11128  | [[projects:trr393:b08|B08]]    | Impact of chronobiological modulation on sleep/EEG rhythm and immune-metabolic parameters | Marburg\\ Münster | Carsten Culmsee\\ Kay Juengling|
| 11131  | [[projects:trr393:c01|C01]]    | Emotion regulation and depressive course of illness | Dresden\\ Marburg|Katharina Förster\\ Stefan G. Hofmann |
| 11132  | [[projects:trr393:c02|C02]]    | Expectation violation and reward sensitivity in psychological interventions modifying course of illness in acute depression | Marburg | Winfried Rief\\ Igor Nenadić |
| 11133  | [[projects:trr393:c03|C03]]    | Social interaction-based mental training in major depression | Dresden | Philipp Kanske |
| 11134  | [[projects:trr393:c04|C04]]    | Cortical synaptic strength and behavioural rhythms in bipolar depression | Dresden\\ \\ Münster |Philipp Ritter\\ Allan Young\\ Joachim Groß|